The first push of the US COVID-19 vaccination campaign averted an estimated 140,000 deaths and more than 3 million infections by early May, saving $625 billion to $1.4 trillion, suggests an observational study yesterday in Health Affairs.In the first known study to evaluate the effects of state-level vaccination campaigns, a team led by Indiana University-Purdue University Indianapolis (IUPUI) researchers modeled the number of COVID-19 deaths that would have occurred from Dec 21, 2020, to May 9, 2021, had it not been for vaccines.The difference between the actual number of deaths and the modeling data provided an estimate of the number of deaths prevented.All states benefit, some more than othersVaccines prevented an estimated 139,393